Grapefruit juice
Question:
On Fri, 07 Aug 1998 22:37:08 -0800, tim…@best.com (kcd) wrote: >when i was 38 i started having pvc’s (ectopic beats), which i HATE AND >DESPISE. i don’t want to hate them, but sometimes they are so bad, i >can’t help it—-they trigger panic attacks and i just….don’t….want to >have them. they haven’t gotten worse as i’ve aged, but they sure haven’t >gotten better. my ekg, cholesterol, b/p, b/g, etc. are all normal, and i >am a woman of size. i exercise a lot. i LOVE exercise, especially in the >water. i’m going to start some strength training (free weights) next >month.
Hi Kathleen, I understand how you feel about the ectopic beats. I have had those occasionally since my early twenties. As I got older they became more frequent and noticable. They seemed to be more predominant after highly stressful situations, and during the premenstrual phase. I’ve been fortunate that I haven’t had them trigger an anxiety attack. (But I had the racing heartbeat then, which I think was either the cause or the result of the panic attack. This was apparently a meno symptom for me, as I’d never experienced it before peri-menopause… and now that I’m in a fairly symptom-less phase, have not had either the panic attacks, racing heartbeat OR the PVCs — for about a year.) >thinking of the Change in a positive light, i’m excited about cronehood. >i’m a violinist and i suspect this may be the beginning of my most >fruitful years personally and artistically.
I hope so! During peri-menopause I have had a decrease in creativity, which has been disappointing and annoying. But I’ve had some flashes of what post-menopausal zesting may be like and anticipate finding that I’m more creative then. >– >I think it’s going to be a long time until American society accepts fat >people. Dieting has been elevated into a religion, a new religion, and >only the thin are "good" and saved. The new messiah is any weight-loss >expert. And if you couple religious fervor and righteousness with desire >and pressure [to lose weight], you have a recipe for dismissive posturing. > - C. K. Grinnell
Thanks for posting this quote. I am really bothered by the anti-fat bigotry in society and particularly in the medical community, and would like to see stronger efforts being made to counteract and remove that bigotry. Lianne To reply by e-mail, remove "seesig." from my address. No spam, no announcements, no commercial e-mail, no mailing lists.
Response:
J Prescott wrote:
<snip> > BC Pills (UK brands) containing ethinylestradiol: > BiNovum,Brevinor, Conova 30, Femodene,Loestrin…et al. > Others contain oestrogen in the form of Mestranol,Oestradiol,Oestriol, > Quinestradol and Quinestrol. > While reading through the warnings and side-effects for many of these > I noticed that, apart from all the usual ones, some of these > oestrogens distort the readings of THYROID function tests. > This may be of interest to anyone with a possible thyroid dysfunction > who is also using hormones.
I was told that hormones, such as birth control pills, would interfere with thyroid absorption, so if I chose to use BCP, I would need a larger dose of Synthroid. — -~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~- -Grey- who no longer has to worry about such stuff… -~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~-
Response:
kcd wrote: > hi asm folks, > this is a delurk/intro. i’m kathleen, i’m gonna be 43 in september, and i > am really awakening to my perimenopausal experience. i am newly married > for the 2nd time and i have teenagers 15 and 13 years old….and 6 cats. > (i, like, rescue them. i am very soft-hearted when it comes to cats.)
<snip> Welcome! I am always happy to see another cat person around. — -~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~- -Grey- Owned by Nick and Thai, tolerated (barely) by Uno (Uno is my SO’s cat!) -~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~-
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>From: Karen Kay <ka…@wordwrite.com> >Date: 8/8/98 11:48 AM Eastern Daylight Time >Message-id: >Anee Bear <aneeb…@aol.com> wrote: >> Ooops I was interrupted while typing that last one…….. >> it should say not to use birth control while using HRT or ERT. >Does it really say this?! Or does it say ‘birth control pills’? >(No wonder so many meno babies are born…) >Karen > ka…@wordwrite.com
Ahhhh, it says birth control PILLS. Sorry. I really screwed up all the way around on that one. Guess I need to keep that killfile tape across my mouth, eh? But, it does say……as an answer to the question: Will ERT or HRT make it possible for me to become pregnant again? A.No. Neither ERT nor HRT affects fertility. Once you enter menopause you can no longer become pregnant. However, if you are still having menstrual periods when you begin taking ERT or HRT, it is possible to become pregnant. In that case, it is advisable to use a barrier method of birth control until your healthcare provider tells you it is no longer necessary. You must not take birth control pills while you are using ERT or HRT. I found the answer to this question very interesting… Q. Will my periods return when I take HRT? A. Women who take a progestin along with estrogen may experience regular monthly bleeding. Although this bleeding seems a lot like a menstrual period, it is not the same. It is referred to as "withdrawal bleeding", because it occurs when the progestin part of your therapy is stopped. Withdraw bleeding is usually light and not uncomfortable, but if it concerns you at all, talk about it with your healthcare provider.Some women find that "withdrawal bleeding" stops in a few months or up to a year after they begin HRT. Hmmm….I wonder if they would think 6 or 7 years is too long? I had stopped my periods for 6 months when my GYN put me on Provera……I am still having periods years later. And I wonder if I were to stop taking it if I would stop having periods. He said when I was using Provera and I stopped having my periods I would truly be in menopause. It ain’t happened yet. 
Anee:) (Who remembers those wonderful 6 months like it was yesterday…..Mmmm….<s>)
Response:
Grapefruit can suppress cytochrome P450 and Phase I liver detoxification. When this occurs, damage may result from drugs or toxins remaining in the body too long. One study found that only 8 oz of juice per day suppressed elimination of one drug, cyclosporin, in 6 out of 14 healthy adults. – Hide quoted text — Show quoted text -In article <35CBC4D1.E213E…@pacbell.net> Grey <Astra…@pacbell.net> writes: >From: Grey <Astra…@pacbell.net> >Subject: Re: Grapefruit juice >Date: Fri, 07 Aug 1998 20:24:01 -0700 >Pat Kight wrote: ><snip>> Grapefruit juice (but not orange juice or other juices, AFAIK) >contains >> substances known as flavinoids which can change the way your body reacts >> to specific classes of drugs, including calcium-channel blockers and >> some drugs used in AIDS therapy and organ transplant post-op treatment. ><snip> >Citrus juices are also known to be dangerous when combined with any drug >that has precautions about irritating the stomach, such as some NSAIDS. >The acid in the juices interacts with the irritants in the drug, and can >cause damage to the stomach lining. According to a friend of mine who >is a nurse, the best thing to take with any drug is a big glass of >water, unless the directions specify not to. >– >-~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~- >-Grey- >-~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~-
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And it can double or even triple the half life of Viagra. Ed – Hide quoted text — Show quoted text -m*e**htu*rtnos…@azstarnet.com wrote in message … >Grapefruit can suppress cytochrome P450 and Phase I liver detoxification. >When this occurs, damage may result from drugs or toxins >remaining in the body too long. One study found that only 8 oz of juice per >day suppressed elimination of one drug, cyclosporin, in 6 out of 14 healthy >adults. >In article <35CBC4D1.E213E…@pacbell.net> Grey <Astra…@pacbell.net> writes: >>From: Grey <Astra…@pacbell.net> >>Subject: Re: Grapefruit juice >>Date: Fri, 07 Aug 1998 20:24:01 -0700 >>Pat Kight wrote: >><snip>> Grapefruit juice (but not orange juice or other juices, AFAIK) >>contains >>> substances known as flavinoids which can change the way your body reacts >>> to specific classes of drugs, including calcium-channel blockers and >>> some drugs used in AIDS therapy and organ transplant post-op treatment. >><snip> >>Citrus juices are also known to be dangerous when combined with any drug >>that has precautions about irritating the stomach, such as some NSAIDS. >>The acid in the juices interacts with the irritants in the drug, and can >>cause damage to the stomach lining. According to a friend of mine who >>is a nurse, the best thing to take with any drug is a big glass of >>water, unless the directions specify not to. >>– >>-~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~- >>-Grey- >>-~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~-
Response:
>While reading through the warnings and side-effects for many of these >I noticed that, apart from all the usual ones, some of these >oestrogens distort the readings of THYROID function tests. >This may be of interest to anyone with a possible thyroid dysfunction >who is also using hormones. >Joanna
Sorry for my ignorance Joanna, but all this is very new to me. I just started taking Prempro because I was thrown into perimenopause after having one ovary completely removed and the other partially removed. 1) but what is an oestrogen? 2)are there oestrogens in Prempro? 3)I also take synthroid, do you know it the Prempro will distort the Thyroid Function tests? thanks so much, for this and all the other information that I rec’d in this news group. I’ve been turning my friend on to this newsgroup and to the web page. shari
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On 8 Aug 1998 05:10:55 GMT, hypo…@aol.com (Hypoint) wrote: – Hide quoted text — Show quoted text ->Wendy wrote: >>Do we know if grapefruit juice has an affect on orally administered hormones >>> >the way it does on some other drugs? I am referring to the caution not to >>> >take >>> >medications with grapefruit juice because of the dangerous enhancement to >>the >>> >drugs effects that can happen? >Pat Kight wrote: >>In searching for a reference, I discovered an entire Web site dedicated >>to the subject: >>http://www.powernetdesign.com/grapefruit/index.htm >(snip) >>To bring this back around to the subject at hand: among the drugs listed >>under "miscellaneous interactions" are ethinyl estradiol/17B-estradiol. >>I *believe* these estradiols are used for birth control — can anyone >>confirm that? Are they used in HRT? >Thank you Pat. >HRT: >ethinyl estradiol: Estinyl >17b-estradiol: Climara, Estrace, Estraderm, Estring, Vivelle >Do not have corresponding information for birth control pills.
BC Pills (UK brands) containing ethinylestradiol: BiNovum,Brevinor, Conova 30, Femodene,Loestrin…et al. Others contain oestrogen in the form of Mestranol,Oestradiol,Oestriol, Quinestradol and Quinestrol. While reading through the warnings and side-effects for many of these I noticed that, apart from all the usual ones, some of these oestrogens distort the readings of THYROID function tests. This may be of interest to anyone with a possible thyroid dysfunction who is also using hormones. Joanna
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><HTML><PRE>Subject: intro >From: tim…@best.com (kcd) >Date: Sat, Aug 8, 1998 02:37 EDT >Message-id: <timbre-0708982237090…@dynamic55.pm02.san-rafael.b>est.com> >hi asm folks,this is a delurk/intro.
> i’m kathleen, i’m gonna be 43 in september, and i >am really awakening to my perimenopausal >experience.
Hi Kathleen! I’m glad I’m not the only one with a house full of cats … five here … all from strays. I think I keep our grocery store in business just from the purchase of litter and food. And as I have mentioned to some in here, I also feed raccoons who live in our yard and the female just recently brought out three babies …. all scampering around her like little puppies!! You have a very positive attitude about your peri symptoms and looking forward to more posts from you. Violinist? Fantastic!!! Hey, I can play chopsticks on the piano, does that count? No? Darn!!! : ) Louise
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On Sat, 8 Aug 1998 10:21:13 -0400, "Shari Serxner" <shari.serx…@gte.net> wrote: >>While reading through the warnings and side-effects for many of these >>I noticed that, apart from all the usual ones, some of these >>oestrogens distort the readings of THYROID function tests. >>This may be of interest to anyone with a possible thyroid dysfunction >>who is also using hormones. >>Joanna >Sorry for my ignorance Joanna, but all this is very new to me. I just >started taking Prempro because I was thrown into perimenopause after having >one ovary completely removed and the other partially removed.
First, DON’T WORRY, Shari. You are in a different position to a woman who is intact. I was talking about birth control pills which contain different forms and dosages of the drug, oestrogen (US spelling estrogen) from Prempro. The discussion we are having here is very much a learning exercise. I was quoting from a directory of medicines and drugs which lists contra-indications and side-effects. I’m not medically qualified and I was just throwing up the information as a point of interest. >1) but what is an oestrogen?
I may have confused you with my English spelling. Oestrogen is the female hormone produced by the ovaries (from cholestrol) and in the adrenal glands. Production switches on at puberty and runs down during peri-menopause. In the case of surgery, such as you have undergone, it has been switched off very suddenly and that is why you have been prescribed Prempro. You say you have half an ovary, and you still have your adrenal glands, so it could well be that in a year or so, you may feel like allowing your body to take over again. Oestrogen naturally occurs in three forms within the female body, Each predominates at different times in a woman’s life. >2)are there oestrogens in Prempro?
Yes. It contains oestrogens which are produced, in laboratories, from the urine of pregnant mares. It also contains progestogen which is necessary if you still have a uterus (womb) as you need to have a period to keep the lining of your womb healthy. >3)I also take synthroid, do you know it the Prempro will distort the Thyroid >Function tests?
I cannot answer this. If you were tested and diagnosed before your operation, my guess would be that you have absolutely nothing to worry about. >thanks so much, for this and all the other information that I rec’d in this >news group. >I’ve been turning my friend on to this newsgroup and to the web page. >shari
PLEASE, don’t worry about either your thyroid tests and medication, or Prempro which is most certainly NOT one of the birth control pills I was talking about. There is a very good book which explains female hormones and the menopause. It is by Dr Susan Love and in the UK it is called The Hormone Dilemma. (I apologise, the USA name escapes my foggy memory). She explains a very complicated subject very well, in my opinion. Lastly, welcome to asm and I am so pleased that you and your friend are finding helpful information here and on Pat’s excellent web site. Best wishes Joanna – Hide quoted text — Show quoted text –
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Good morning, Kathleen! Hope you stay around–we need a violinist! Best wishes to you on your new marriage. You sound like you have an interesting full life, with kids and cats. Anyway, I wish you would keep posting–and your exercise program is admirable! JackieJ (I play the piano and take voice lessons!) – Hide quoted text — Show quoted text -kcd wrote: > hi asm folks, > this is a delurk/intro. i’m kathleen, i’m gonna be 43 in september, and i > am really awakening to my perimenopausal experience. i am newly married > for the 2nd time and i have teenagers 15 and 13 years old….and 6 cats. > (i, like, rescue them. i am very soft-hearted when it comes to cats.) > when i was 38 i started having pvc’s (ectopic beats), which i HATE AND > DESPISE. i don’t want to hate them, but sometimes they are so bad, i > can’t help it—-they trigger panic attacks and i just….don’t….want to > have them. they haven’t gotten worse as i’ve aged, but they sure haven’t > gotten better. my ekg, cholesterol, b/p, b/g, etc. are all normal, and i > am a woman of size. i exercise a lot. i LOVE exercise, especially in the > water. i’m going to start some strength training (free weights) next > month. > my other peri symptoms are hot flashes (power surges….), > irritability/rage, insomnia, occasional swollen ankles, night sweats, and > quasi-uti (urinary tract infection) bladder problems—-what feels like > urethral ultrasensitivity (but that has been going on for the last 8 > years). i was on progesterone-only birth control pills for the last 6 or > so years (with a couple of 6-month breaks in there), so i am only finding > out this summer if i even have periods. my last period barely happened. > so i’m going to ask my nurse-practitioner for a FSH test. > i enjoy reading your posts. > thinking of the Change in a positive light, i’m excited about cronehood. > i’m a violinist and i suspect this may be the beginning of my most > fruitful years personally and artistically. > back to lurking, > kathleen > — > I think it’s going to be a long time until American society accepts fat > people. Dieting has been elevated into a religion, a new religion, and > only the thin are "good" and saved. The new messiah is any weight-loss > expert. And if you couple religious fervor and righteousness with desire > and pressure [to lose weight], you have a recipe for dismissive posturing. > – C. K. Grinnell
– -=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=- http://www.public.usit.net/jackiej/ "Fate goes forth from within us." ~Rilke. -=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
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hi asm folks, this is a delurk/intro. i’m kathleen, i’m gonna be 43 in september, and i am really awakening to my perimenopausal experience. i am newly married for the 2nd time and i have teenagers 15 and 13 years old….and 6 cats. (i, like, rescue them. i am very soft-hearted when it comes to cats.) when i was 38 i started having pvc’s (ectopic beats), which i HATE AND DESPISE. i don’t want to hate them, but sometimes they are so bad, i can’t help it—-they trigger panic attacks and i just….don’t….want to have them. they haven’t gotten worse as i’ve aged, but they sure haven’t gotten better. my ekg, cholesterol, b/p, b/g, etc. are all normal, and i am a woman of size. i exercise a lot. i LOVE exercise, especially in the water. i’m going to start some strength training (free weights) next month. my other peri symptoms are hot flashes (power surges….), irritability/rage, insomnia, occasional swollen ankles, night sweats, and quasi-uti (urinary tract infection) bladder problems—-what feels like urethral ultrasensitivity (but that has been going on for the last 8 years). i was on progesterone-only birth control pills for the last 6 or so years (with a couple of 6-month breaks in there), so i am only finding out this summer if i even have periods. my last period barely happened. so i’m going to ask my nurse-practitioner for a FSH test. i enjoy reading your posts. thinking of the Change in a positive light, i’m excited about cronehood. i’m a violinist and i suspect this may be the beginning of my most fruitful years personally and artistically. back to lurking, kathleen — I think it’s going to be a long time until American society accepts fat people. Dieting has been elevated into a religion, a new religion, and only the thin are "good" and saved. The new messiah is any weight-loss expert. And if you couple religious fervor and righteousness with desire and pressure [to lose weight], you have a recipe for dismissive posturing. – C. K. Grinnell
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Wendy wrote: >Do we know if grapefruit juice has an affect on orally administered hormones >> >the way it does on some other drugs? I am referring to the caution not to >> >take >> >medications with grapefruit juice because of the dangerous enhancement to >the >> >drugs effects that can happen? Pat Kight wrote: >In searching for a reference, I discovered an entire Web site dedicated >to the subject: >http://www.powernetdesign.com/grapefruit/index.htm
(snip) >To bring this back around to the subject at hand: among the drugs listed >under "miscellaneous interactions" are ethinyl estradiol/17B-estradiol. >I *believe* these estradiols are used for birth control — can anyone >confirm that? Are they used in HRT?
Thank you Pat. HRT: ethinyl estradiol: Estinyl 17b-estradiol: Climara, Estrace, Estraderm, Estring, Vivelle Do not have corresponding information for birth control pills. Wendy hypo…@aol.com
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Ooops I was interrupted while typing that last one…….. it should say not to use birth control while using HRT or ERT. Anee
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Hmm…this made me wonder, since I’m a big grapefruit juice fan. I found this page on the subject: http://www.geocities.com/Area51/Shire/7917/ While it doesn’t mention HRT specifically, it does make me wonder if there’s any harm in the mixing. Xav Hypoint <hypo…@aol.com> wrote in article <1998080715011300.LAA18…@ladder01.news.aol.com>… – Hide quoted text — Show quoted text -> Just a thought and question that occurred to me as I was taking a sip of Ruby > Red grapefruit juice. > Do we know if grapefruit juice has an affect on orally administered hormones > the way it does on some other drugs? I am referring to the caution not to take > medications with grapefruit juice because of the dangerous enhancement to the > drugs effects that can happen? > Wendy > hypo…@aol.com
Response:
Pat Kight wrote:
<snip>> Grapefruit juice (but not orange juice or other juices, AFAIK) contains > substances known as flavinoids which can change the way your body reacts > to specific classes of drugs, including calcium-channel blockers and > some drugs used in AIDS therapy and organ transplant post-op treatment.
<snip> Citrus juices are also known to be dangerous when combined with any drug that has precautions about irritating the stomach, such as some NSAIDS. The acid in the juices interacts with the irritants in the drug, and can cause damage to the stomach lining. According to a friend of mine who is a nurse, the best thing to take with any drug is a big glass of water, unless the directions specify not to. — -~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~- -Grey- -~~*~~-~~*~~-~~*~~-~~*~~-~~*~~-*~~-*~~-*~~-
Response:
- Hide quoted text — Show quoted text ->Subject: Re: Grapefruit juice >From: Pat Kight <kig…@ucs.orst.edu> >Date: 8/7/98 10:49 AM Pacific Daylight Time >Message-id: <35CB3E16.1A6AB…@ucs.orst.edu> >Anee Bear wrote: >> >From: hypo…@aol.com (Hypoint) >> >Do we know if grapefruit juice has an affect on orally administered >hormones >> >the way it does on some other drugs? I am referring to the caution not to >> >take >> >medications with grapefruit juice because of the dangerous enhancement to >the >> >drugs effects that can happen? >> WHAT???!!! <Gasp> >> I never heard this…..please explain what you mean? >Grapefruit juice (but not orange juice or other juices, AFAIK) contains >substances known as flavinoids which can change the way your body reacts >to specific classes of drugs, including calcium-channel blockers and >some drugs used in AIDS therapy and organ transplant post-op treatment. >Although much of the publicity about this effect has focused on the >negative side of grapefruit juice-drug interaction, some clinicians are >exploring the effect as a way of increasing the effectiveness of certain >drugs in people who aren’t responding to treatment. >In searching for a reference, I discovered an entire Web site dedicated >to the subject: >http://www.powernetdesign.com/grapefruit/index.htm >… which should tell you all you need to know. The site appears to have >been put together by a >pharmacy student, and the citations seem solid. >To bring this back around to the subject at hand: among the drugs listed >under "miscellaneous interactions" are ethinyl estradiol/17B-estradiol. >I *believe* these estradiols are used for birth control — can anyone >confirm that? Are they used in HRT? >And our old friend, Viagra, is also listed under "potential interactions >…" >–Pat Kight >kig…@peak.org
Wow, very interesting. Thanks,Pat. Strange that orange juice does not do the same thing though.Hmm… I think I read that estradiol is used in for birth control, and yes my Climira patch is estradiol transdermal system. Although the little book that comes with the patch says you should not use estradiol while using HRT or ERT. Anee:)
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>From: hypo…@aol.com (Hypoint) >Date: Fri, Aug 7, 1998 11:01 EDT >Message-id: <1998080715011300.LAA18…@ladder01.news.aol.com> >Just a thought and question that occurred to me as I was taking a sip of Ruby >Red grapefruit juice. >Do we know if grapefruit juice has an affect on orally administered hormones >the way it does on some other drugs? I am referring to the caution not to >take >medications with grapefruit juice because of the dangerous enhancement to the >drugs effects that can happen? >Wendy >hypo…@aol.com
WHAT???!!! <Gasp> I never heard this…..please explain what you mean? Horrified Anee:0
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Anee Bear wrote: > >From: hypo…@aol.com (Hypoint) > >Do we know if grapefruit juice has an affect on orally administered hormones > >the way it does on some other drugs? I am referring to the caution not to > >take > >medications with grapefruit juice because of the dangerous enhancement to the > >drugs effects that can happen? > WHAT???!!! <Gasp> > I never heard this…..please explain what you mean?
Grapefruit juice (but not orange juice or other juices, AFAIK) contains substances known as flavinoids which can change the way your body reacts to specific classes of drugs, including calcium-channel blockers and some drugs used in AIDS therapy and organ transplant post-op treatment. Although much of the publicity about this effect has focused on the negative side of grapefruit juice-drug interaction, some clinicians are exploring the effect as a way of increasing the effectiveness of certain drugs in people who aren’t responding to treatment. In searching for a reference, I discovered an entire Web site dedicated to the subject: http://www.powernetdesign.com/grapefruit/index.htm … which should tell you all you need to know. The site appears to have been put together by a pharmacy student, and the citations seem solid. To bring this back around to the subject at hand: among the drugs listed under "miscellaneous interactions" are ethinyl estradiol/17B-estradiol. I *believe* these estradiols are used for birth control — can anyone confirm that? Are they used in HRT? And our old friend, Viagra, is also listed under "potential interactions …" –Pat Kight kig…@peak.org
Response:
Just a thought and question that occurred to me as I was taking a sip of Ruby Red grapefruit juice. Do we know if grapefruit juice has an affect on orally administered hormones the way it does on some other drugs? I am referring to the caution not to take medications with grapefruit juice because of the dangerous enhancement to the drugs effects that can happen? Wendy hypo…@aol.com
