Pred not working as well this time
Question:
Pred is poison to your body so your immune system is going to attack it with everything it can. Ken: Where did you ever get this idea? Prednisone is very similar to a hormone your own body makes: cortisol, produced by the adrenal glands. It would make no sense for your body to mount an immune response against a hormone it makes itself and which is necessary to sustain life (cortisol maintains blood pressure, etc.)
na funny but when i read aloud ken’s response re prednisone my husband said aloud..just about word for word what you wrote<g..thanks for clearing THAT one up…pred is far from being a ‘poison"..BUT..i am thinking its odd that a number of people are coming on here saying its not working for them now..thats what happened to me..could there be a bad batch of pred around??? take care annie
Response:
That didn’t even occur to me. I suppose it is possible. I will have to ask my doc to see how likely he thinks it is. (Of course he could be wrong.) We are very much at the mercy of others. I hate that. Jason
– Hide quoted text — Show quoted text – Pred is poison to your body so your immune system is going to attack it with everything it can. Ken: Where did you ever get this idea? Prednisone is very similar to a hormone your own body makes: cortisol, produced by the adrenal glands. It would make no sense for your body to mount an immune response against a hormone it makes itself and which is necessary to sustain life (cortisol maintains blood pressure, etc.) na funny but when i read aloud ken’s response re prednisone my husband said aloud..just about word for word what you wrote<g..thanks for clearing THAT one up…pred is far from being a ‘poison"..BUT..i am thinking its odd that a number of people are coming on here saying its not working for them now..thats what happened to me..could there be a bad batch of pred around??? take care annie
Response:
- Hide quoted text — Show quoted text – Pred is poison to your body so your immune system is going to attack it with everything it can. Ken: Where did you ever get this idea? Prednisone is very similar to a hormone your own body makes: cortisol, produced by the adrenal glands. It would make no sense for your body to mount an immune response against a hormone it makes itself and which is necessary to sustain life (cortisol maintains blood pressure, etc.) na funny but when i read aloud ken’s response re prednisone my husband said aloud..just about word for word what you wrote<g..thanks for clearing THAT one up…pred is far from being a ‘poison"..BUT..i am thinking its odd that a number of people are coming on here saying its not working for them now..thats what happened to me..could there be a bad batch of pred around??? take care annie
There could be a number of reasons why prednisone doesn’t work as well over time. For some individuals their disease may be getting worse and the same dose of steroids may not be enough to bring it under control. Also many people may develop a tolerance to prednisone and a higher dose is needed to get a therapeutic response, this happens with a number of drugs. This has absolutely nothing to do with the body mounting an immune response to prednisone though.
Response:
In article I just started my 3rd cycle of pred since I was diagnosed with CD 1 1/2 years ago. The other two times I took it, it worked very quickly; between a few hours and 1 day. It has been 3 days now, and I have blood and pain still. Not like the last times. My question: Have you long time CD patients found that you have progressively had to take more and more pred as the years have gone on to acheive the same result? I am currently on 40 mg pred. Thanks, Jason
I"ve been on Pred for PG since August of last year. Got up to 60 mg and around Christmas, along with being on Cellcept, the insomnia was HORRIBLE. I didn’t sleep more than 5-10 hrs in more than a week and finally they lowered the CellCept and pred and I got back to sleeping well. When I started the Pred+Cellcept, the PG started healing up like a rocket and I thought it would close in and be done, but it didn’t. Went back on pred + cellcept and it didn’t work and then pred and Imuran and that isn’t working. PG is stalled, but 90% healed in from where I started. BUT, when PG was at worst, I did notice that it seemed to be at worst in dead of winter, Jan-March and was most benign and healing during summer into late fall, when I played as much golf as I could-being out in Sun as much as I could. I should also say that immune wise as kid I got everything up to being in 3rd grade. After that, I couldn’t get more than a cold here and there till I was in college. Nothing. And I’m still that way, even on the immunosupressives, Cellcept, tacrolimus, imuran, prednisone etc. I’ve had some virus that lasted 24-48 hrs with headache and a bit of fever, but nothing more than that. My kid comes home with colds from school and myh wife gets them, I don’t. Even my doc’s are amazed that on the drugs I get so little. But yet I’ve got the damn PG…which has ruled me for some 18 yrs… — Regards, Jim Polaski "The measure of a man is what he will do while expecting that he will get nothing in return!" Macintosh for productivity. Linux for servers. Palm/Visor for mobility. Windows to feed the Black Hole in your IT budget Windows-the computer you need, Macintosh-The computer you Want!ant!i
